MilliporeSigma
All Photos(3)

F3510

Sigma-Aldrich

D-(−)-Fructose

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):
D-Levulose, Fruit sugar
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1239004
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

corn

product line

BioReagent

assay

≥99%

form

powder

optical activity

[α]25/D -91.3 to -87.7 °, c = 5% (w/v) in water

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

impurities

≤0.05% Glucose (enzymatic)

mp

119-122 °C (dec.) (lit.)

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1

InChI key

BJHIKXHVCXFQLS-UYFOZJQFSA-N

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General description

Fructose is a monosaccharide. It is present in fruits and vegetables. Fructose is the major carbohydrate in the diet. It binds with glucose to form sucrose. Excessive intake of fructose is associated with obesity, type 2 diabetes and cardiovascular disease.

Application

D-(-)-Fructose has been used for metabolite determination. It has also been used as a component of cultural media.

Packaging

100, 500 g in poly bottle
5 kg in poly drum

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Nutritional Biochemistry (1999)
Fructose and cardiometabolic health: what the evidence from sugar-sweetened beverages tells us
Malik VS and Hu FB
Journal of the American College of Cardiology, 66(14), 1615-1624 (2015)
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
Testing, 10(3), e0119053-e0119053 (2015)
Jiyoung Kim et al.
Nature communications, 11(1), 5436-5436 (2020-10-30)
Harmful effects of high fructose intake on health have been widely reported. Although fructose is known to promote cancer, little is known about the underlying mechanisms. Here, we found that fructose triggers breast cancer metastasis through the ketohexokinase-A signaling pathway.
Jee-Hwan Oh et al.
Cell host & microbe, 25(2), 273-284 (2019-01-20)
The mammalian intestinal tract contains a complex microbial ecosystem with many lysogens, which are bacteria containing dormant phages (prophages) inserted within their genomes. Approximately half of intestinal viruses are derived from lysogens, suggesting that these bacteria encounter triggers that promote

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