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M6020

Sigma-Aldrich

D-(+)-Mannose

powder, BioReagent, suitable for cell culture

Synonym(s):
D-Mannopyranose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1564373
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

biological source

plant (Spruce, Birch or Beech Wood, Glucose)

Quality Level

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

mp

133-140 °C (lit.)

solubility

H2O: 50 mg/mL

application(s)

agriculture

SMILES string

OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1

InChI key

WQZGKKKJIJFFOK-QTVWNMPRSA-N

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General description

Mannose is an aldohexose carbohydrate. It is isomer of glucose with varying C2 position configuration.[44] Majority of mannose is synthesised from its epimer glucose.[45] It is part of the glycans present in endoplasmic reticulum (ER)/Golgi.[45]

Application

D-(+)-Mannose has been used:
  • as a reference standard in monosaccharide analysis and quantification from sea squirts Ascidiella aspersa
[69]
  • as a medium component for the selection of P898012 sorgum seeds transfected with Agrobacterium
  • [48]
  • in segmented filamentous bacterium (SFB) medium supplement for culturing human cell lines
  • [17]
    Mannose is an aldohexose carbohydrate. This product may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation.

    Packaging

    25, 100, 500 g in poly bottle

    Biochem/physiol Actions

    Mannose may be used to study the effects of exogenous mannose on in vitro processes such as glycosylation. cis-Golgi glycoproteins have high mannose and are prone to Endoglycosidase H or peptide N-glycosidase (N-glycanase) digestion.[46]

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves

    Certificate of Analysis

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    Certificate of Origin

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