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D8388

Sigma-Aldrich

Dimethyl pimelimidate dihydrochloride

powder

Synonym(s):
Dimethyl pimelinediimidate dihydrochloride, DMP
Linear Formula:
[CH3OC(=NH)CH2CH2]2CH2 · 2HCl
CAS Number:
Molecular Weight:
259.17
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

form

powder

Quality Level

reaction suitability

reagent type: cross-linking reagent

solubility

H2O: 10 mg/mL

storage temp.

−20°C

SMILES string

Cl.Cl.COC(=N)CCCCCC(=N)OC

InChI

1S/C9H18N2O2.2ClH/c1-12-8(10)6-4-3-5-7-9(11)13-2;;/h10-11H,3-7H2,1-2H3;2*1H

InChI key

LRHXBHUTQWIZTN-UHFFFAOYSA-N

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General description

Dimethyl pimelimidate dihydrochloride is a homobifunctional cross-linking reagent used in crosslinking, protein interaction and protein modification. It typically reacts with primary amines in the pH range 7.0-10.0 to form amidine bonds.

Application

Dimethyl pimelimidate dihydrochloride has been used to develop a technique for isolating Enterocytozoon bieneusi spores directly from human stool samples with a high degree of purity, which opens up new approaches for studying this parasite.

Caution

The reagent is readily hydrolyzed at neutral pH.

Other Notes

Note that the amidine linkage preserves original primary amine positive charge. Incorporates a seven atom linker.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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