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reagent grade, 98%

Tris(2-hydroxyethyl)amine, 2,2′,2′′-Nitrilotriethanol
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


reagent grade

vapor density

5.14 (vs air)

vapor pressure

0.01 mmHg ( 20 °C)




viscous liquid

autoignition temp.

600 °F

expl. lim.

8.5 %

refractive index

n20/D 1.485 (lit.)

useful pH range


pKa (25 °C)



190-193 °C/5 mmHg (lit.)


17.9-21 °C (lit.)


soluble 149 g/L at 20 °C (completely)


1.124 g/mL at 25 °C (lit.)

SMILES string




InChI key


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Triethanolamine can be used as:
  • A nitrogen precursor in the preparation of carbon dot derived nanomaterials.
  • A cross-linking agent in the synthesis of methylaluminoxane pre-catalysts applicable in the polymerization of ethylene.
  • A reducing agent to synthesize Ag nanoparticles of biological importance.


1, 4 kg in poly bottle
20 kg in steel drum
25 g in poly bottle

Storage Class Code

10 - Combustible liquids



Flash Point(F)

354.2 °F - closed cup

Flash Point(C)

179 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the boiling point of Product T58300, Triethanolamine?

    The boiling point is not determined by Sigma-Aldrich, but is reported to be 190-193°C at a reduced pressure of 5mm Hg.

  4. Product T58300, Triethanolamine, was received as a solid and it usually arrives as a liquid. Is the product still acceptable?

    Yes, the product is still acceptable. Triethanolamine has a melting point of 17.9-21°C, which is near room temperature. The item ships under ambient conditions. As a result, it may arrive as a solid when exposed to cold temperatures (especially during the winter months). Gentle heating in a warm water bath will easily convert the material back into its expected viscous liquid appearance.

  5. What kind of gloves would be recommended when working with Product T58300, Triethanolamine?

    When working with the material, we would recommend neoprene, nitrile or butyl gloves. For example, the Best® butyl, ChemMaster or N-DEX®  gloves.

  6. How can I dilute Product T58300, Triethanolamine?

    According to the chemicals encyclopedia published by the Royal Society of Chemistry (which we also offer as product Z705322), triethanolamine is expected to be miscible with water, methanol or acetone.

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Carbonization conditions influence the emission characteristics and the stability against photobleaching of nitrogen doped carbon dots
Xiong Y, et al.
Nanoscale, 9(32), 11730-11738 (2017)
Friederike Saaber et al.
Cell reports, 26(6), 1473-1488 (2019-02-07)
Phosphorylation of heptahelical receptors is thought to regulate G protein signaling, receptor endocytosis, and non-canonical signaling via recruitment of β-arrestins. We investigated chemokine receptor functionality under phosphorylation-deficient and β-arrestin-deficient conditions by studying interneuron migration in the embryonic cortex. This process
Xiaoxuan Liu et al.
Bioconjugate chemistry, 22(12), 2461-2473 (2011-11-08)
With the aim of developing dendrimer nanovectors with a precisely controlled architecture and flexible structure for DNA transfection, we designed PAMAM dendrimers bearing a triethanolamine (TEA) core, with branching units pointing away from the center to create void spaces, reduce
Kostas Karatasos et al.
Macromolecular bioscience, 12(2), 225-240 (2011-12-08)
In this work we report, compare and discuss the results obtained from fully atomistic molecular dynamics simulations of generations 4, 5, and 6 of PAMAM-based dendrimers having NH(3) and triethanolamine as cores, forming complexes with a short interfering RNA (siRNA)
Liviu Ungur et al.
Journal of the American Chemical Society, 134(45), 18554-18557 (2012-11-01)
A toroidal magnetic moment in the absence of conventional total magnetic moment is observed in a {Dy(6)} ring. The reason for the net toroidal arrangement of the local magnetic moments is the high symmetry of the complex in combination with

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