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C5042

Sigma-Aldrich

Cresyl Violet acetate

certified by the Biological Stain Commission

Synonym(s):
9-Amino-5-imino-5H-benzo[a]phenoxazine acetate salt
Empirical Formula (Hill Notation):
C18H15N3O3
CAS Number:
Molecular Weight:
321.33
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

Quality Level

grade

certified by the Biological Stain Commission

form

powder

composition

Dye content, ~70%

mp

140-143 °C (lit.)

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

CC(O)=O.Nc1cc2OC3=CC(=N)C=CC3=Nc2c4ccccc14

InChI

1S/C16H11N3O.C2H4O2/c17-9-5-6-13-14(7-9)20-15-8-12(18)10-3-1-2-4-11(10)16(15)19-13;1-2(3)4/h1-8,17H,18H2;1H3,(H,3,4)

InChI key

ORIKHDNZZCTIAD-UHFFFAOYSA-N

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Application

Cresyl Violet acetate has been used in Nissl staining of sections from spinal cord and brain.

Packaging

10 g in glass bottle

Suitability

Certified for Nissl staining of paraffin sections of spinal cord and brain and to stain cartilage and mast cell granules.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Xuerui Ran et al.
Journal of chemical neuroanatomy, 98, 97-103 (2019-04-25)
The paraventricular nucleus (PVN) of the hypothalamus is an important center in regulating the functions of internal organs, and it is the key nucleus for coordinating endocrine, behavior and autonomic stress responses. Dopamine receptors are widely expressed in the hypothalamus
Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury.
Najafzadeh N, et al.
Neural Regeneration Research, 8, 3365-3372 (2013)
Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-? Clearance.
Gontier G, et al.
The Journal of Neuroscience, 35, 11500-11513 (2015)
Coronavirus-induced demyelination of neural pathways triggers neurogenic bladder overactivity in a mouse model of multiple sclerosis.
McMillan MT, et al.
American Journal of Physiology: Renal Physiology, 307, F612-F622 (2014)
Mohd Salman et al.
Disease models & mechanisms, 13(8) (2020-06-17)
Pramipexole (PPX), a D2-like receptor agonist, is generally used in the treatment of Parkinson's disease and restless leg syndrome. Its neuroprotective effects have been shown against various neurological disorders. Recent research work has demonstrated that PPX exerts neuroprotection through mitochondria.

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