C1879
Choline chloride
≥98%
Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride
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All Photos(3)
About This Item
Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
Molecular Weight:
139.62
Beilstein/REAXYS Number:
3563126
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
synthetic
Quality Level
assay
≥98%
form
powder or crystals
technique(s)
cell culture | mammalian: suitable
color
colorless to white
mp
302-305 °C (dec.) (lit.)
SMILES string
[Cl-].C[N+](C)(C)CCO
InChI
1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
InChI key
SGMZJAMFUVOLNK-UHFFFAOYSA-M
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General description
Choline chloride is the synthetic form of vitamin B4, choline and is a common poultry feed.
Application
Choline chloride has been used:
- as a substrate for measuring choline oxidase enzyme activity using fluorescence measurements
- as a component of non-physiological buffers for testing calcium based inhibition of cytochrome c oxidaseP
- as a component of perfusate solution for studying arterial pressure in jejunum samples
Biochem/physiol Actions
Choline chloride treatment of radish seeds modulates phosphatidylcholine and phosphatidylethanolamine levels. It elicits hepatoprotective effects and modulates methyl carbon based metabolic pathways.
Substrates
Choline acetyltransferase substrate
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat
Lucas ML and Morrison JD
Physiological Reports, 3(5) (2015)
Evaluation of polyherbal formulation and synthetic choline chloride on choline deficiency model in broilers: implications on zootechnical parameters, serum biochemistry and liver histopathology
Selvam R, et al.
Asian-Australasian Journal of Animal Sciences, 31(11), 1795-1795 (2018)
Effect of choline chloride on the lipid content and composition in the leaves of principal magnetically-oriented radish types
Novitskaya GV, et al.
Russian Journal of Plant Physiology, 51(3), 361-371 (2004)
Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
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PLoS ONE, 12(2), e0171080-e0171080 (2017)
Rapid enzymatic method for the determination of phosphoryl choline using the fluorescence of the enzyme choline oxidase. Sequential determination of choline and phosphorylcholine in milk powder for children
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