A8094

L-Arginine

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (S)-2-Amino-5-guanidinopentanoic acid
• Linear Formula: H₂NC(=NH)NH(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 74-79-3
• Molecular Weight: 174.20
• Beilstein/REAXYS Number: 1725413
• EC Number: 200-811-1
• MDL number: MFCD00002635
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24891316
• NACRES: NA.26

Properties

• product name: L-Arginine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%
• biological source: non-animal source
• Quality Level: 300
• agency: USP/NF; meets EP testing specifications; meets USP testing specifications
• product line: BioXtra
• assay: 98.5-101.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 222 °C (dec.) (lit.)
• solubility: H₂O: 100 mg/mL
• application(s): agriculture; peptide synthesis; pharmaceutical (small molecule)
• SMILES string: N[C@@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
• InChI key: ODKSFYDXXFIFQN-BYPYZUCNSA-N
• Gene Information: human ... NOS1(4842) , NOS2(4843) ; rat ... Ppm1a(24666)

Description

Application

L-Arginine has been used:

• as a Roswell park memorial institute medium (RPMI) media component in the isolation and culture of peripheral blood mononuclear cells (PBMCs)
• as a RPMI media component for tissue culture
• in DMEM medium for the identification and quantification of phosphorylation sites by stable isotope labeling by amino acids in cell culture (SILAC) and LCMS/MS

Biochem/physiol Actions

L-Arginine is a conditionally essential amino acid, that play a vital role in the production of nitric oxide. It acts as a precursor for the synthesis of polyamines, agmatine and urea. L-Arginine is usually essential in children and non-essential in adults.

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)