95220

Ergocalciferol

≥98.0% (sum of enantiomers, HPLC)

• Synonym(s): Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D₂
• Empirical Formula (Hill Notation): C₂₈H₄₄O
• CAS Number: 50-14-6
• Molecular Weight: 396.65
• Beilstein/REAXYS Number: 1916682
• EC Number: 200-014-9
• MDL number: MFCD00166988
• UNSPSC Code: 12352205
• eCl@ss: 34058017
• PubChem Substance ID: 57653661
• NACRES: NA.79

Properties

• biological source: synthetic
• assay: ≥98.0% (sum of enantiomers, HPLC)
• form: powder
• optical activity: [α]20/D +105±2°, c = 4% in ethanol
• color: colorless to white
• mp: 114-118 °C (lit.); 114-118 °C
• storage temp.: 2-8°C
• SMILES string: CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
• InChI key: MECHNRXZTMCUDQ-RKHKHRCZSA-N
• Gene Information: human ... VDR(7421)

Description

General description

Ergocalciferol is one of the two forms of supplemental vitamin D available. It is a fat-soluble vitamin.

Ergocalciferol or viosterol is obtained from irradiated ergosterol. It represents plant source of vitamin D.

Application

Ergocalciferol has been used as a standard to measure vitamin D3 levels in food samples.

Biochem/physiol Actions

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two form of vitamin D which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

Ergocalciferol (vitamin D2) has less potential than cholecalciferol (vitamin D3) in treating vitamin deficiency related disorders in humans. Supplementation of adequate dose of vitamin D2 prevents infantile rickets and is capable of curing adult osteomalacia.

Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311,H330,H372
• pcodes: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges