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18887

Millipore

Byzen Pro Protein A resin

suitable for affinity chromatography

form

suspension

Quality Level

technique(s)

affinity chromatography: suitable

mean particle size

70 μm

storage temp.

2-8°C

Application

Byzen Pro Protein A resin is an affinity chromatography medium in which a novel Protein A mutant is used as a ligand. Conventional protein A resins use strongly acidic buffers to elute antibodies, exposing the target antibody to the risks of aggregation and decreased activities. In contrast, this temperature- responding Byzen Pro Protein A resin allows antibodies to be eluted under neutral pH by a simple temperature change. This eliminates any risk of aggregation and decreased activity of the antibody, improving manufacturing efficiency for pharmaceutical antibodies.

Features and Benefits

Typical Product Profile:
Bead Structure, Cross-linked polyvinyl alcohol, Mean Particle Size 70 μm, Max. Back Pressure 0.3 MPa, Flow Rate (Recommended) 125-250 cm/h, pH Range (Recommended) pH 6-8, Ligand: Recombinant Protein A mutant, Ligand Immobilization: Multiple ligation, Dynamic Binding Capacity (20 cm column): 26 g/L (250 cm/h) 34 g/L (125 cm/h), Total Binding Capacity 40 g/L, Binding Temperature Below 10°C, Eluting Temperature 37 to 40°C, Mode of Temperature Change: Conventional heat exchange system can be used.

Legal Information

Byzen Pro is a trademark of Nomadic Bioscience Co., Ltd

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Origin

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SDS

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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