137262

Tricine

EMPROVE^® EVOLVE

• Synonym(s): Tricine, N-[Tris(hydroxymethyl)methyl]glycine
• Linear Formula: (HOCH₂)₃CNHCH₂CO₂H
• CAS Number: 5704-04-1
• Molecular Weight: 179.17
• Beilstein/REAXYS Number: 1937804
• MDL number: MFCD00004277
• UNSPSC Code: 12161700

Properties

• biological source: synthetic
• Quality Level: 400
• product line: EMPROVE^® EVOLVE
• form: powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, heavy metals, trace metals, residual solvents, tested (; Endotoxin, microbial, and trace metals; tested)
• pH: 7.4-8.8
• useful pH range: 7.4-8.8
• pKa (25 °C): 8.1
• pKa: 8.1
• suitability: suitable for manufacturing use
• storage temp.: 2-30°C
• SMILES string: OCC(CO)(CO)NCC(O)=O
• InChI: 1S/C6H13NO5/c8-2-6(3-9,4-10)7-1-5(11)12/h7-10H,1-4H2,(H,11,12)
• InChI key: SEQKRHFRPICQDD-UHFFFAOYSA-N

Description

Application

Buffer component for separation of low molecular weight peptides.

Buffer component for separation of low molecular weight peptides.Tricine is a biological buffer often referred to as a “Good′s” buffer. The pKa of Tricine is 8.1 which makes Tricine is a good candidate for biological applications that require pH control above physiological. Tricine is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable