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PHR1012

Supelco

Methylparaben

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Methyl 4-hydroxybenzoate, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN
Linear Formula:
HOC6H4CO2CH3
CAS Number:
Molecular Weight:
152.15
Beilstein:
509801
EC Number:
MDL number:
PubChem Substance ID:
E Number:
E218
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. M1650000
traceable to USP 1432005

API family

parabens

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

125-128 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

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This Item
143200547889M1650000
Methylparaben Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1012

Methylparaben

Methylparaben United States Pharmacopeia (USP) Reference Standard

USP

1432005

Methylparaben

Methyl Paraben PESTANAL®, analytical standard

Supelco

47889

Methyl Paraben

Methyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard

M1650000

Methyl parahydroxybenzoate

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

analytical standard

grade

pharmaceutical primary standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

storage temp.

2-30°C

storage temp.

-

storage temp.

2-30°C

storage temp.

-

Quality Level

300

Quality Level

-

Quality Level

100

Quality Level

-

General description

Methylparaben is an antifungal and antibacterial agent, widely used as a preservative in cosmetics, pharmaceuticals, food and beverages.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Methylparaben may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase sequential injection chromatography (SIC) technique and high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0280 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

334.4 °F

Flash Point(C)

168 °C


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