Skip to Content
MilliporeSigma
All Photos(1)

Documents

91719

Supelco

Trifluoroacetic anhydride

for GC derivatization, LiChropur™, ≥99.0% (GC)

Synonym(s):

TFAA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CF3CO)2O
CAS Number:
407-25-0
Molecular Weight:
210.03
Beilstein/REAXYS Number:
746197
EC Number:
206-982-9
MDL number:
MFCD00000416
UNSPSC Code:
12000000
PubChem Substance ID:
329770069
NACRES:
NA.22

grade

for GC derivatization

Quality Level

100

vapor pressure

6.28 psi ( 20 °C)

assay

≥99.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations
reagent type: derivatization reagent
reaction type: Esterifications

technique(s)

gas chromatography (GC): suitable (ECD)

refractive index

n20/D 1.3 (lit.)

bp

39.5-40 °C (lit.)

mp

−65 °C (lit.)

density

1.511 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

InChI key

QAEDZJGFFMLHHQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Learn more in the Product Information
Suitable for derivatization of amines, aryl amines, phenolic amines, primany amines, tertiary aromatic amines, amino acids, aminoalkylphosphoric acids, 2-aminoethylphosphoric acid, 1-hydroxy-2-aminoethylphosponic acid, amphetamine, beta blocker drugs, creatinine, desipramine, dopamine, glutathione, glycol (MOPEG), guanidine drugs, histidine, n-hydroxy-2-fluorenylacetamide, n-hydroxylamines, hydroxy acids, p-hydroxyamphetamine, 4-hydroxycoumarins, p-hydroxynorephedrine, hydroxysteroids, 5-hydroxytryptamine, indoles, Iodoamino acids, carbaryl and hydroxylated metabolites, metanephrine, methylphenidate, norepinephrine, normetanephrine, peptide amide, phenformin, phenols, phentermine, phenylthiohydantoin amino acid, propranolol, sulfonamides, sulfonylureas, thiamine, vanillymandelic acid, trisubstituted ureas and urea.

Other Notes

For the protection of prim. and sec. amines; derivatives are more volatile
Reagent for cabethoxy, butyl ester, n-methyl, methyl ester, di(trifluoroacetyl), hexafluoroisopropyl ester, acetyl or trifluoroacetyl phenylthihydantoins, trifluoroacetyl (2-hydroxy-2-methyl)ethyl, n-trifluoroacetyl, trifluoroacetyl (TFA), trifluoroacetamide, 4-trifluoromethyl-2, 6-diamino-1,3,5-triazineacetyl and trifluoroacetyl vanillin.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

supp_hazards

EUH014

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 2

ppe

Faceshields, Gloves, Goggles

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH1823
BCCF1808
BCCD0260
BCCC2215
BCCB4093

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Phosphonoglycan. A major polysaccharide constituent of the amoeba plasma membrane contains 2-aminoethylphosphonic acid and 1-hydroxy-2-aminoethylphosphonic acid.
E D Korn et al.
The Journal of biological chemistry, 248(6), 2257-2259 (1973-03-25)
Mass fragmentography of creatinine proposed as a reference method.
I Björkhem et al.
Clinical chemistry, 23(11), 2114-2121 (1977-11-01)
Determination of phenformin in biological fluids using chemical ionization mass spectrometry.
S B Matin et al.
Biomedical mass spectrometry, 1(5), 320-322 (1974-10-01)
T.W. Greene et al.
Protective Groups in Organic Synthesis null
Quantitative determination of guanethidine and other guanido-containing drugs in biological fluids by gas chromatography with flame ionization detection and multiple ion detection.
J H Hengstmann et al.
Analytical chemistry, 46(1), 34-39 (1974-01-01)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service