68069

Hippuric acid

analytical standard

• Synonym(s): N-Benzoylglycine, Benzoylaminoacetic acid
• Linear Formula: C₆H₅CONHCH₂COOH
• CAS Number: 495-69-2
• Molecular Weight: 179.17
• Beilstein/REAXYS Number: 1073987
• EC Number: 207-806-3
• MDL number: MFCD00002692
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: analytical standard
• assay: ≥97.5% (GC)
• shelf life: limited shelf life, expiry date on the label
• mp: 187-191 °C (lit.)
• application(s): clinical testing
• format: neat
• SMILES string: OC(=O)CNC(=O)c1ccccc1
• InChI: 1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
• InChI key: QIAFMBKCNZACKA-UHFFFAOYSA-N

Description

General description

Hippuric acid, the glycine conjugate of benzoic acid, is formed via a biotransformation process. From scientific literature, it is reported to be found as an excretory product in urine. Hippuric acid is also known to be catabolically synthesized from benzene-type aromatic compounds, believed to be originated from various factors such as environmental exposures, basic human liver metabolism of protein catabolism, cyclic sugar type-compounds, quinic acid, etc.

Application

Hippuric acid may be used as an analytical reference standard for the quantification of the analyte in the following:

• Human biological fluids using high-performance liquid chromatography (HPLC) with UV detection.
• Human and rat urine samples using gas chromatography–mass spectrometry (GC–MS).
• Human urine samples using GC equipped with a flame ionization detector.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable