230464

Thionyl chloride

ReagentPlus^®, ≥99%

• Linear Formula: SOCl₂
• CAS Number: 7719-09-7
• Molecular Weight: 118.97
• Beilstein: 1209273
• EC Number: 231-748-8
• MDL number: MFCD00011449
• PubChem Substance ID: 24853806
• NACRES: NA.21

Properties

• vapor pressure: 97 mmHg ( 20 °C)
• Quality Level: 200
• product line: ReagentPlus^®
• assay: ≥99%
• form: liquid
• refractive index: n20/D 1.518 (lit.)
• bp: 79 °C (lit.)
• mp: −105 °C (lit.)
• density: 1.631 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): 59.0-60.2%
• SMILES string: ClS(Cl)=O
• InChI: 1S/Cl2OS/c1-4(2)3
• InChI key: FYSNRJHAOHDILO-UHFFFAOYSA-N

Description

General description

Thionyl chloride is an inorganic acid chloride mainly used to prepare carboxylic acid chlorides from carboxylic acids.

Application

Thionyl chloride may be used in the following processes:

• To facilitate the synthesis of indenones from 3-hydroxyindanones via dehydroxylation.
• Surface modification of amorphous carbon nanotubes (α-CNTs) in stearic acid-dichloromethane solution.
• To functionalize silica gel for thioacetalization of aldehydes.
• Conversion of tert-butyl esters to acid chlorides.
• Conversion of aliphatic and aromatic sulfoxides to sulfides in the presence of triphenylphosphine.
• As an activator to generate ketenes in-situ for preparing 2-azetidinones.

Packaging

5 mL in glass bottle

100, 100, 500 mL in Sure/Seal™

1, 2.5, 10 L

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS05,GHS06
• Signal Word: Danger
• Hazard Statements: H302 - H314 - H331 - H335
• Precautionary Statements: P261 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH014 - EUH029
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves