MilliporeSigma
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146072

Sigma-Aldrich

N,N′-Methylenebis(acrylamide)

99%

Synonym(s):
Bis-acrylamide
Linear Formula:
(H2C=CHCONH)2CH2
CAS Number:
Molecular Weight:
154.17
EC Number:
MDL number:
PubChem Substance ID:
Flavis number:
7.107
NACRES:
NB.22

vapor density

5.31 (vs air)

Quality Level

assay

99%

form

powder

mp

>300 °C (lit.)

solubility

water: soluble 20 g/L at 20 °C

storage temp.

2-8°C

SMILES string

C=CC(=O)NCNC(=O)C=C

InChI

1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)

InChI key

ZIUHHBKFKCYYJD-UHFFFAOYSA-N

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General description

N,N′-Methylenebis(acrylamide) is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel. It is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.[56]

Application

N,N′-Methylenebis(acrylamide) has been used in gel preparation.[54] It has also been used as a test compound for studying the biochemical isolation of insoluble Tau in transgenic mouse models of tauopathy by examining the two main isolation methods sarkosyl and formic acid extraction.[55]
Cross-linking agent for preparation of polyacrylamides.

Packaging

100, 500 g in poly bottle

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Muta. 1B

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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