W310700

Vanillin

≥97%, FCC, FG

• Synonym(s): 4-Hydroxy-3-methoxybenzaldehyde, Vanillic aldehyde
• Linear Formula: 4-(HO)C₆H₃-3-(OCH₃)CHO
• CAS Number: 121-33-5
• Molecular Weight: 152.15
• FEMA Number: 3107
• Beilstein: 472792
• EC Number: 204-465-2
• Council of Europe no.: 107
• MDL number: MFCD00006942
• PubChem Substance ID: 24901469
• Flavis number: 5.018

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Halal; Kosher
• reg. compliance: EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR 182.60; FDA 21 CFR 182.90
• vapor density: 5.3 (vs air)
• vapor pressure: >0.01 mmHg ( 25 °C)
• description: Agency/Method; meets purity specifications of JECFA
• Assay: ≥97%
• form: powder or crystals
• bp: 170 °C/15 mmHg (lit.)
• mp: 81-83 °C (lit.)
• solubility: DMSO: soluble(lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• Organoleptic: creamy; sweet; vanilla
• SMILES string: COc1cc(C=O)ccc1O
• InChI: 1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
• InChI key: MWOOGOJBHIARFG-UHFFFAOYSA-N

Description

General description

Vanillin is the world′s most popular flavor and fragrance compound. It may be a potential agent of pharmacological importance and useful for the treatment of major depressive disorder. Eumelanin-inspired core derived from vanillin has been found to be useful for the synthesis of eumelanin-inspired small molecules and polymer via Sonogashira cross coupling. Biotechnology-based vanillin synthesis using ferulic acid, eugenol and glucose as substrates and bacteria, fungi and yeasts as microbial production hosts has been reported. Vanillin, a polar aromatic flavor compound, is present in the extracts of natural and artificial vanilla flavors.

Application

Vanillin is suitable for use in a study to evaluate its sensitizing effect on a tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant human cervical cancer cell line, HeLa.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 319.6 - 321.4 °F - closed cup
• Flash Point(C): 159.8 - 160,8 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves