D99250

Diethyl 2,2-diethoxyethylphosphonate

95%

• Synonym(s): Diethyl phosphonoacetaldehyde diethyl acetal, NSC 407851, NSC 77101
• Linear Formula: (CH₃CH₂O)₂CHCH₂P(O)(OCH₂CH₃)₂
• CAS Number: 7598-61-0
• Molecular Weight: 254.26
• Beilstein/REAXYS Number: 1785614
• EC Number: 231-504-0
• MDL number: MFCD00009236
• UNSPSC Code: 12352108
• PubChem Substance ID: 24894353
• NACRES: NA.22

Properties

• assay: 95%
• form: liquid
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.430 (lit.)
• bp: 146-149 °C/14 mmHg (lit.)
• density: 1.052 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CCOC(CP(=O)(OCC)OCC)OCC
• InChI: 1S/C10H23O5P/c1-5-12-10(13-6-2)9-16(11,14-7-3)15-8-4/h10H,5-9H2,1-4H3
• InChI key: LUQYELQXRPNKRY-UHFFFAOYSA-N

Description

Application

Reactant for synthesis of:

• α,β-Alkenal derivatives by two-carbon homologation
• Lower rim-phosphonylated rexorcinol calix[4]arenes by condensation reactions
• α-Phosphovinyl radicals via a radical trapping sequence
• Inhibitors of reverse transcriptase via 1,3-dipolar cycloadditions

Reactant for Friedel-Crafts reactions

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter