158763

Methyl diethylphosphonoacetate

97%

• Synonym(s): Methyl P,P-diethylphosphonoacetate, (Methoxycarbonylmethyl) diethoxyphosphine oxide, NSC 147757, [(Methoxycarbonyl)methyl]phosphonic acid diethyl ester
• Linear Formula: (C₂H₅O)₂P(O)CH₂CO₂CH₃
• CAS Number: 1067-74-9
• Molecular Weight: 210.16
• Beilstein/REAXYS Number: 1782397
• EC Number: 213-938-2
• MDL number: MFCD00009081
• UNSPSC Code: 12352108
• PubChem Substance ID: 24849773
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.433 (lit.)
• bp: 127-131 °C/9 mmHg (lit.)
• density: 1.145 g/mL at 25 °C (lit.)
• functional group: ester; phosphonate
• SMILES string: CCOP(=O)(CC(=O)OC)OCC
• InChI: 1S/C7H15O5P/c1-4-11-13(9,12-5-2)6-7(8)10-3/h4-6H2,1-3H3
• InChI key: CTSAXXHOGZNKJR-UHFFFAOYSA-N

Description

Application

Reactant or reagent for:

• Synthesis of branches allylic fluorides
• Regioselective Diels-Alder reactions to yield antibiotic building blocks
• Substituted thiophenes and furans synthesis for treatment of type 2 diabetes
• Stereoselective Diels-Alder cycloaddition reactions
• Synthesis of pyridone alkaloids with neuritogenic activity
• Modification of botulinum neurotoxin serotype A protease inhibitors
• Synthesis of immunosuppressive cyclopentanediol derivatives

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter