766305

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite

95%

• Synonym(s): Bis(2-cyanoethoxy)(diisopropylamino)phosphine, Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine
• Empirical Formula (Hill Notation): C₁₂H₂₂N₃O₂P
• CAS Number: 102690-88-0
• Molecular Weight: 271.30
• MDL number: MFCD00797597
• PubChem Substance ID: 329767224
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• form: liquid
• refractive index: n20/D 1.465
• density: 1.039 g/mL at 25 °C
• storage temp.: −20°C
• SMILES string: CC(C)N(C(C)C)P(OCCC#N)OCCC#N
• InChI: 1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3
• InChI key: LDHWBEHZLFDXCU-UHFFFAOYSA-N

Description

General description

Useful phosphorylating reagent used in oligonucleotide synthesis for adding a terminal phosphate group to the 3′ or 5′ hydroxyl.

Application

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite may be used as a phosphitylating agent during the multi-step synthesis of (-)-1L-chiro-inositol 2,3,5-trisphosphate starting from L-quebrachitol.

Packaging

1, 5 g in glass bottle

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331 - H315 - H319
• Precautionary Statements: P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): 165.0 °F
• Flash Point(C): 73.9 °C