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379212

Sigma-Aldrich

Hexamethyldisilazane

ReagentPlus®, 99.9%

Synonym(s):
1,1,1,3,3,3-Hexamethyldisilazane, HMDS
Linear Formula:
(CH3)3SiNHSi(CH3)3
CAS Number:
Molecular Weight:
161.39
Beilstein:
635752
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

product line

ReagentPlus®

assay

99.9%

form

liquid

refractive index

n20/D 1.407 (lit.)

bp

125 °C (lit.)

SMILES string

C[Si](C)(C)N[Si](C)(C)C

InChI

1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3

InChI key

FFUAGWLWBBFQJT-UHFFFAOYSA-N

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General description

Hexamethyldisilazane (HDMS) is an organoslicon compound.HDMS is a colorless liquid used as a reagent and precursor in organic synthesis and organometallic chemistry.

Application

Used in
  • condensation reactions of heterocyclic compounds, such as derivatives of xanthine
[49]
  • adhesion promoter for photoresist in photolithography
  • electron microscopy, as an alternative to critical point drying during sample preparation
  • [50]
  • pyrolysis-gas chromatography-mass spectrometry, in order to enhance detectability of compounds with polar functional groups.
  • [51]

    Packaging

    25, 100 mL in Sure/Seal™

    Legal Information

    ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

    Pictograms

    FlameSkull and crossbones

    Signal Word

    Danger

    Hazard Classifications

    Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2

    Storage Class Code

    3 - Flammable liquids

    WGK

    WGK 2

    Flash Point(F)

    52.5 °F - closed cup

    Flash Point(C)

    11.4 °C - closed cup

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves

    Certificate of Analysis

    Enter Lot Number to search for Certificate of Analysis (COA).

    Certificate of Origin

    Enter Lot Number to search for Certificate of Origin (COO).

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