MilliporeSigma
All Photos(3)

300977

Sigma-Aldrich

(R)-4-Benzyl-2-oxazolidinone

99%

Empirical Formula (Hill Notation):
C10H11NO2
CAS Number:
Molecular Weight:
177.20
Beilstein:
4782551
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

powder

optical activity

[α]18/D +64°, c = 1 in chloroform

mp

88-90 °C

SMILES string

O=C1N[C@@H](CO1)Cc2ccccc2

InChI

1S/C10H11NO2/c12-10-11-9(7-13-10)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,11,12)/t9-/m1/s1

InChI key

OJOFMLDBXPDXLQ-SECBINFHSA-N

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Application

Used in the synthesis of HIV protease inhibitors.
(R)-4-Benzyl-2-oxazolidinone may be used as a starting material in the synthesis of enantiopure carbocyclic nucleosides. It may also be used as a chiral auxiliary in the enantioselective synthesis of (2R,2′S)-erythro-methylphenidate.
Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta.

Packaging

1, 5, 25 g in glass bottle

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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