14580

N_α,N_α-Bis(carboxymethyl)-L-lysine hydrate

≥97.0% (TLC), for peptide synthesis

• Synonym(s): (S)-N-(5-Amino-1-carboxypentyl)iminodiacetic acid
• Empirical Formula (Hill Notation): C₁₀H₁₈N₂O₆ · xH₂O
• CAS Number: 941689-36-7
• Molecular Weight: 262.26 (anhydrous basis)
• Beilstein/REAXYS Number: 9141770
• MDL number: MFCD24387945
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57647179
• NACRES: NA.22

Properties

• product name: N_α,N_α-Bis(carboxymethyl)-L-lysine hydrate, ≥97.0% (TLC)
• Quality Level: 100
• assay: ≥97.0% (TLC)
• form: powder
• reaction suitability: reaction type: solution phase peptide synthesis
• application(s): peptide synthesis
• SMILES string: O.NCCCC[C@H](N(CC(O)=O)CC(O)=O)C(O)=O
• InChI: 1S/C10H18N2O6.H2O/c11-4-2-1-3-7(10(17)18)12(5-8(13)14)6-9(15)16;/h7H,1-6,11H2,(H,13,14)(H,15,16)(H,17,18);1H2/t7-;/m0./s1
• InChI key: WTVPNZLAZFGAFK-FJXQXJEOSA-N

Description

General description

Nα,Nα-Bis(carboxymethyl)-L-lysine hydrate is a synthetic amino acid used in solution phase peptide synthesis.

Application

<ul>
<li><strong>N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate in Biosensor Development:</strong> Zhang et al. explored the use of functionalized graphene oxide for the fabrication of biosensors aimed at detecting paraoxon, a nerve agent, where N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate is used as a part of the step-by-step process to anchor onto the GO-based materials (Zhang et al., 2014).</li>
<li><strong>Protein Purification Enhancements:</strong>N,N-Bis(carboxymethyl)-l-lysine hydrate (ANTA) is used in the synthesis of superparamagnetic Fe3O4/Au nanoparticles as a conjugating agent. It facilitates the attachment of Co2+ ions to the surface-modified Fe3O4/Au nanoparticles, resulting in the formation of Fe3O4/Aun and ndash;ANTA and ndash;Co2+ nanoparticles (Zhang et al., 2013).</li>
</ul>

Analysis Note

may contain up ~2 mol water and ~10% inorganic salts

Other Notes

Tricarboxylic acid used for preparing chelating resins employed for the chromatography of proteins

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)