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Key Documents

359688

Sigma-Aldrich

Boc-Lys-OH

99%

Synonym(s):

Nα-(tert-Butoxycarbonyl)-L-lysine, Nα-Boc-L-lysine

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About This Item

Linear Formula:
NH2(CH2)4CH(COOH)NHCOOC(CH3)3
CAS Number:
Molecular Weight:
246.30
Beilstein/REAXYS Number:
4252546
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

solid

optical activity

[α]20/D +22°, c = 2 in methanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

~205 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N[C@@H](CCCCN)C(O)=O

InChI

1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1

InChI key

DQUHYEDEGRNAFO-QMMMGPOBSA-N

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Application

Boc-Lys-OH (Nα-Boc-L-lysine) can be used as a building block to synthesize:
  • A heterotrifunctional peptide-based linker molecule applicable as a bio-labeling reagent.
  • Lysine derivatives of azamacrocycle and anthraquinone.
  • Boc-Lys(Bn4-DTPA)-OH, a precursor to synthesize diethylene triamine pentaacetic acid (DTPA) containing peptides.
  • A ferrocene-amino acid conjugate which is used in developing chemical warfare agent (CWA) sensor.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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