推薦產品
用途
sufficient for 200 tests (UV)
特點
This kit is sufficient for up to 100 assays of 3-hydroxybutyric acid (BOH) and up to 100 assays of acetoacetic acid (AcAc) in 96 well plates.
檢測方法
colorimetric
相關疾病
endocrinological disorders, diabetes; neonatal diseases; pediatric diseases; cancer
儲存溫度
−20°C
一般說明
酮体 3-羟基丁酸 (BOH) 和乙酰乙酸 (AcAc) 主要在肝脏中由脂肪酸氧化生成 ，正常情况下在尿液和血液中浓度较低。血液中酮体浓度升高可能导致代谢性酸中毒，这与糖尿病、儿童期低血糖、生长激素缺乏症、酒精或水杨酸盐中毒以及先天性代谢缺陷相关。
應用
酮体测定法已用于测量人肝癌细胞系 HepG2 培养基中酮体的释放。
特點和優勢
兼容高通量的操作系统。
適合性
可用于检测血清、血浆、尿液及其他生物样品中的酮体（乙酰乙酸和3-羟基丁酸）。
原則
在本试剂盒中，使用基于 3-羟基丁酸脱氢酶催化反应的酶分析法测定 AcAc 和 BOH 水平，其中在 340 nm 处测定的 NADH 吸光度更改与 AcAc 和 BOH 浓度直接相关。
儲存類別代碼
10 - Combustible liquids
從最近期的版本中選擇一個：
分析證明 (COA)
Lot/Batch Number
客戶也查看了
Role of beta-hydroxybutyric acid in diabetic ketoacidosis: A review.
Stojanovic, et al.
The Canadian Veterinary Journal. La Revue Veterinaire Canadienne, 52(4), 426-426 (2011)
Zachary M Augur et al.
Frontiers in nutrition, 5, 91-91 (2018-10-24)
Introduction: Temozolomide (TMZ) is part of the standard of care for treating glioblastoma multiforme (GBM), an aggressive primary brain tumor. New approaches are needed to enhance therapeutic efficacy and reduce toxicity. GBM tumor cells are dependent on glucose and glutamine
Role of β-hydroxybutyrate, its polymer poly-β-hydroxybutyrate and inorganic polyphosphate in mammalian health and disease.
Dedkova E N and Lothar A B
Frontiers in Physiology, 5, 260-260 (2014)
Kim J Shimy et al.
Journal of the Endocrine Society, 4(7), bvaa062-bvaa062 (2020-07-16)
According to the carbohydrate-insulin model of obesity, an elevated insulin-to-glucagon ratio in response to a high-carbohydrate diet directs metabolic fuels toward storage, resulting in lower circulating energy. To determine differences in total circulating energy post-meal related to dietary carbohydrate. Ancillary
Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes.
Kanikarla M, et al.
Free Radical Biology & Medicine, 95, 268-277 (2016)
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務