推薦產品
形狀
powder
包裝
pkg of 1 × 10 mg (860517P-10mg)
pkg of 1 × 25 mg (860517P-25mg)
pkg of 1 × 5 mg (860517P-5mg)
製造商／商標名
Avanti Research™ - A Croda Brand
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
OC[C@]([H])(NC(CCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C35H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(39)36-33(32-37)34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-34,37-38H,3-27,29,31-32H2,1-2H3,(H,36,39)/b30-28+/t33-,34+/m0/s1
InChI 密鑰
ICWGMOFDULMCFL-QKSCFGQVSA-N
一般說明
甲酰胺合成可通过以下两种方法进行介导：通过鞘氨醇或鞘氨醇水解的挽救途径；或通过二氢神经酰胺形成的从头途径。在结构上，神经酰胺具有鞘氨醇碱基，即通过酰胺键与脂肪酸连接的长链氨基醇。
應用
C17神经酰胺(d18:1/17:0)已被用于：
- 通过色谱与负离子电喷雾电离串联质谱联用定量测定心肌神经酰胺的内标物，
- 作为串联质谱(MS/MS)的内标物
- 作为鞘磷脂合酶2的底物
生化／生理作用
神经酰胺在调节各种细胞过程（如衰老和凋亡）中起关键作用。它们直接参与皮肤细胞的增殖和分化并调节皮肤屏障功能。基于神经酰胺的类似物是潜在的抗肿瘤药，被视为抑癌脂质。
包裝
5 mL 棕色螺旋盖玻璃瓶l (860517P-10mg)
5 mL 棕色螺旋盖玻璃瓶l (860517P-25mg)
5 mL 棕色螺旋盖玻璃瓶l (860517P-5mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
也與該產品經常一起購買
產品號碼
描述
訂價
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Ye-Ryung Kim et al.
Experimental & molecular medicine, 51(11), 129-129 (2019-11-05)
The endoplasmic reticulum (ER) is not only important for protein synthesis and folding but is also crucial for lipid synthesis and metabolism. In the current study, we demonstrate an important role of ceramide synthases (CerS) in ER stress and NAFLD
Takuya Takeichi et al.
The Journal of clinical investigation, 130(2), 890-903 (2019-11-02)
The corneocyte lipid envelope, composed of covalently bound ceramides and fatty acids, is important to the integrity of the permeability barrier in the stratum corneum, and its absence is a prime structural defect in various skin diseases associated with defective
Insulin resistance, ceramide accumulation, and endoplasmic reticulum stress in human chronic alcohol-related liver disease
Longato L, et al.
Oxidative Medicine and Cellular Longevity, 2012 (2012)
André F Nascimento et al.
Life sciences, 88(23-24), 1031-1038 (2011-04-05)
Leptin resistance has been associated with cardiac lipotoxicity; however, whether leptin resistance is a risk factor associated with cardiac lipotoxicity at different time points in diet-induced obesity is unclear. The objective of this study was to evaluate this relationship. Male
Nadine Beckmann et al.
International journal of molecular sciences, 20(24) (2019-12-15)
Farber disease is a rare lysosomal storage disorder resulting from acid ceramidase deficiency and subsequent ceramide accumulation. No treatments for Farber disease are clinically available, and affected patients have a severely shortened lifespan. We have recently reported a novel acid
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務