推薦產品
生物源
bovine milk
品質等級
種類
Type III
化驗
≥85% (PAGE)
形狀
lyophilized powder
品質
calcium depleted
分子量
14,178 Da by calculation
濃度
≥85 % protein
技術
indirect ELISA: suitable
雜質
cation traces, tested
溶解度
H2O: soluble 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
正離子痕跡
Ca: ≤0.3 mol/mol
UniProt登錄號
儲存溫度
−20°C
基因資訊
cow ... LALBA(281894)
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相關類別
一般說明
may contain traces of (NH4)2SO4 and sodium phosphateL6010
應用
α-牛乳乳清蛋白已用于：
- 间接酶联免疫吸附测定（ELISA）和竞争性ELISA方法
- Hsp90和HSJ1b结合分析
- 抑制溶菌酶CAP-RAST测定体系
生化／生理作用
α-乳清蛋白是人乳中的主要蛋白。它由含有8个半胱氨酸（可形成二硫键）的单个多肽链组成。α-乳清蛋白可结合包括钙在内的几种金属离子，这被认为有助于从还原的变性形式α-乳清蛋白中再生天然形式的α-乳清蛋白。α-乳清蛋白还具有独特的锌结合位点，其被认为在乳糖合酶复合物的结合中起作用。其成熟蛋白由123个氨基酸残基（14kD）组成，具有1.7埃分辨率的三维结构，包含四个α-螺旋和三链反平行β-折叠。
其可通过改变半乳糖基转移酶的底物特异性以增加乳糖形成的速率；半乳糖基转移酶和 α-乳白蛋白的复合物称为乳糖合酶。
其可通过改变半乳糖基转移酶的底物特异性以增加乳糖形成的速率；半乳糖基转移酶和α-乳白蛋白的复合物称为乳糖合酶。Asp87 或 Asp88 对 Ala 的定点诱变完全消除了强钙结合亲和力，并将乳糖合酶的刺激降低到最大速率的 <3.5%。
品質
可能含微量 (NH4)2SO4 和磷酸钠。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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