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C0406

Sigma-Aldrich

κ-酪蛋白 来源于牛奶

≥70% (PAGE), lyophilized powder

同義詞:

Kappa-Casein

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About This Item

CAS號碼:
9000-71-9
EC號碼:
232-555-1
MDL號碼:
MFCD00081481
分類程式碼代碼:
12352202
NACRES:
NA.61

生物源

bovine milk

品質等級

200

化驗

≥70% (PAGE)

形狀

lyophilized powder

技術

isoelectric focusing (IEF): suitable

儲存溫度

−20°C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

InChI 密鑰

BECPQYXYKAMYBN-UHFFFAOYSA-N

基因資訊

cow ... MKCAS(100531419) , MKCASP(105755569)

一般說明

酪蛋白占牛奶总蛋白的80%。κ-酪蛋白是牛奶中主要的过敏原之一。它是由半乳糖、半乳糖胺和唾液酸组成的糖基化蛋白。以三糖或四糖形式存在，根据连接的寡糖数目表现为不同的亚型。κ-酪蛋白具有疏水性N末端和亲水性C末端区域。

應用

κ-酪蛋白（来源于牛奶）已用于：
  • 作为标准品定量分析酪蛋白浓度，评估菌株水解HM Mozzarella奶酪中酪蛋白的能力
  • 制备LPS缺失母牛牛奶蛋白质以用于淋巴细胞增殖检测
  • 作为反相高效液相色谱法(RP-HPLC)标准品，用于定量分析脱脂牛奶样本中的κ-酪蛋白浓度

生化／生理作用

κ-酪蛋白（来自牛乳）是属于酪蛋白磷蛋白家族的免疫球蛋白E（IgE）结合表位。κ-酪蛋白对酪蛋白胶束悬液的静电和空间稳定性具有重要作用。它可抗钙沉淀，因此可稳定其他酪蛋白。κ-酪蛋白一直是通过基因修饰制造低苯丙氨酸牛奶的研究对象，这对患有苯丙酮尿症(PKU)等代谢性疾病的患者很重要。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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Paramjit S Bansal et al.
Biochemical and biophysical research communications, 340(4), 1098-1103 (2006-01-13)
The caseins (alphas1, alphas2, beta, and kappa) are phosphoproteins present in bovine milk that have been studied for over a century and whose structures remain obscure. Here we describe the chemical synthesis and structure elucidation of the N-terminal segment (1-44)
Mária Baranyi et al.
Journal of biotechnology, 128(2), 383-392 (2006-12-13)
Patients suffering certain metabolic diseases (e.g. phenylketonuria) need a low-phenylalanine diet throughout their lives. Transgenic rabbits were created to express low-phenylalanine kappa-casein in their milk. The aim was to demonstrate for the first time the feasibility of producing a modified
Johanna Roostalu et al.
Cell, 175(3), 796-808 (2018-10-20)
During cell division, mitotic motors organize microtubules in the bipolar spindle into either polar arrays at the spindle poles or a "nematic" network of aligned microtubules at the spindle center. The reasons for the distinct self-organizing capacities of dynamic microtubules
Aprianita Aprianita et al.
The Journal of dairy research, 81(2), 183-192 (2014-03-07)
This experiment was conducted to determine the effects of diets supplemented with cottonseed oil, Acacia mearnsii-condensed tannin extract, and a combination of both on composition of bovine milk. Treatment diets included addition of cottonseed oil (800 g/d; CSO), condensed tannin from
Caterina Villa et al.
Comprehensive reviews in food science and food safety, 17(1), 137-164 (2018-01-01)
Cow milk allergy is one of the most common food allergies in early childhood and often persists through adult life, forcing an individual to a complete elimination diet. Milk proteins are present in uncounted food products, such as cheese, yogurt
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文章

HPLC Analysis of Caseins on BIOshell™ A400 Protein C4

-casein basis (electrophoresis), lyophilized powder; β-Casein from bovine milk, BioUltra, ≥98% (PAGE)

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