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Key Documents

C4832

Sigma-Aldrich

1-磷酸神经酰胺 来源于牛大脑

~95%

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.77

化驗

~95%

品質等級

形狀

powder

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(O)=O)[C@H](O)\C=C\CCCCCCCCCCCCC

InChI

1S/C36H72NO6P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(39)37-34(33-43-44(40,41)42)35(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,34-35,38H,3-28,30,32-33H2,1-2H3,(H,37,39)(H2,40,41,42)/b31-29+/t34-,35+/m0/s1

InChI 密鑰

ZQQLMECVOXKFJK-NXCSZAMKSA-N

相關類別

生化/生理作用

激动剂刺激鞘磷脂代谢的第二信使;可能参与细胞调控和跨膜信号传导。

其他說明

主要含有硬脂酸和神经酸。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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O Boudker et al.
The Journal of biological chemistry, 268(29), 22150-22155 (1993-10-15)
A calcium-dependent ceramide (Cer) kinase was recently detected in human leukemia (HL-60) cells (Kolesnick, R.N., and Hemer, M.R. (1990) J. Biol. Chem. 265, 18803-18808) where it may function in terminating the regulatory effects of Cer, and in synaptic vesicles (Bajjalieh
R Shinghal et al.
Journal of neurochemistry, 61(6), 2279-2285 (1993-12-01)
Recent studies have implicated sphingolipids in a variety of intracellular signaling systems. The finding that a calcium-stimulated ceramide kinase copurifies with neurotransmitter-containing vesicles suggests that ceramide, or one of its metabolites, has a role in neurotransmitter release. As a step
Shaowei Wang et al.
Molecular neurodegeneration, 16(1), 26-26 (2021-04-18)
Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer's disease (AD), but the mechanisms for this association are not clear. The activation of calcium-dependent cytosolic phospholipase A2 (cPLA2) is involved in

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