427572

Lactosyl Ceramide, Bovine

A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL.

• 同義詞: Lactosyl Ceramide, Bovine, Galβ,1,4Glc-Cer, LacCer, LC, LC, Galβ,1,4Glc-Cer, LacCer
• 經驗公式（希爾表示法）: C₅₃H₁₀₁NO₁₃
• CAS號碼: 4682-48-8
• 分子量：: 960.37
• MDL號碼: MFCD00133445
• 分類程式碼代碼: 12352211

屬性

• 品質等級: 100
• 化驗: ≥98% (TLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: colorless
• 溶解度: ethanol: 1 mM; methanol: 1 mM
• 運輸包裝: ambient
• 儲存溫度: −20°C
• InChI: 1S/C48H91NO13/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(53)49-36(37(52)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2)35-59-47-45(58)43(56)46(39(34-51)61-47)62-48-44(57)42(55)41(54)38(33-50)60-48/h29,31,36-39,41-48,50-52,54-58H,3-28,30,32-35H2,1-2H3,(H,49,53)/b31-29+/t36?,37?,38-,39-,41+,42+,43-,44-,45-,46+,47-,48?/m1/s1
• InChI 密鑰: VOZHMDQUIRUFQW-AIRKALMMSA-N

描述

一般說明

A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells.

A neutral glycosphingolipid (GSL) which is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco- series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of p44 MAP kinase. Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase and c-fos expression in human aortic smooth muscle cells.



Molecular weight: 960.4 (based on tricosanyl -23:0)

M.W. 960.4 (based on tricosanoyl - 23:0).

生化／生理作用

Cell permeable: no

Primary Target
A neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

其他說明

Bhunia, A.K., et al. 1997. J. Biol. Chem.272, 15642.
Bhunia, A.K., et al. 1996. J. Biol. Chem.271, 10660.
Zacharias, C., et al. 1994. J. Biol. Chem.269, 13313.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable