全部照片(1)
About This Item
經驗公式(希爾表示法):
C27H44O3
CAS號碼:
分子量::
416.64
Beilstein:
7559394
EC號碼:
MDL號碼:
分類程式碼代碼:
12352205
eCl@ss:
34058003
PubChem物質ID:
NACRES:
NA.79
推薦產品
品質等級
化驗
≥99% (HPLC)
形狀
solid
技術
HPLC: suitable
儲存溫度
−20°C
SMILES 字串
[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
InChI 密鑰
GMRQFYUYWCNGIN-NKMMMXOESA-N
基因資訊
human ... VDR(7421)
尋找類似的產品? 前往 產品比較指南
生化/生理作用
在钙的吸收和沉积中维生素D3的生物活性形式。
在钙的吸收和沉积中维生素D3的生物活性形式。 1α,25-二羟基维生素D3对细胞分化和增殖具有广泛的作用,并可调节免疫应答和中枢神经系统功能。最近的研究表明,1α,25-二羟基维生素D3可作为抵抗包括前列腺癌和结肠癌在内数种恶性肿瘤的化学预防剂,并显示出了与其他抗癌化合物的协同作用。
胆钙化醇是维生素D3的一种失活形式,它在经历各种水平的羟基化后可形成活性的维生素D3类似物。 1α-羟基维生素D3(阿法骨化醇是一种可代谢为1,25-二羟胆钙化醇的合成类似物,它是钙吸收和沉积中维生素D3的生物活性形式。1α,25-二羟基维生素D3对细胞分化和增殖具有广泛的作用,并可调节免疫应答和中枢神经系统功能。最近的研究表明,1α,25-二羟基维生素D3可作为抵抗包括前列腺癌和结肠癌在内数种恶性肿瘤的化学预防剂,并显示出了与其他抗癌化合物的协同作用。
相關產品
產品號碼
描述
訂價
訊號詞
Danger
危險分類
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - STOT RE 1
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
客戶也查看了
Maurizio Cutolo et al.
Vitamins and hormones, 86, 327-351 (2011-03-23)
Epidemiological evidence indicates a significant association between vitamin D deficiency and an increased incidence of autoimmune diseases. The presence of vitamin D receptors (VDRs) in the cells of the immune system and the fact that several of these cells produce
Maria Plesa et al.
Journal of asthma and allergy, 13, 249-264 (2020-09-29)
Airway fibroblasts are major contributors to the histopathological feature of airway remodeling in asthma by their implication in the cell invasiveness and profibrogenic secretory phenotype observed in subepithelial fibrosis. 1,25 Dihydroxy vitamin D3 (1,25(OH)2D3) is an important therapeutic agent that
Vitamin D deficiency reduces the benefits of progesterone treatment after brain injury in aged rats.
Milos Cekic et al.
Neurobiology of aging, 32(5), 864-874 (2009-06-02)
Administration of the neurosteroid progesterone (PROG) has been shown to be beneficial in a number of brain injury models and in two recent clinical trials. Given widespread vitamin D deficiency and increasing traumatic brain injuries (TBIs) in the elderly, we
Moira Cheung et al.
The Journal of clinical endocrinology and metabolism, 98(5), E954-E961 (2013-03-28)
X-linked hypophosphatemic rickets is caused by mutations in PHEX. Even though the disease is characterized by disordered skeletal mineralization, detailed bone densitometric studies are lacking. The aim of the study was to assess volumetric bone mineral density (vBMD) in X-linked
Edwin C Y Chow et al.
Gastroenterology, 146(4), 1048-1059 (2013-12-25)
Little is known about the effects of the vitamin D receptor (VDR) on hepatic activity of human cholesterol 7α-hydroxylase (CYP7A1) and cholesterol metabolism. We studied these processes in mice in vivo and mouse and human hepatocytes. Farnesoid X receptor (Fxr)(-/-)
文章
Vitamin D and Prevention of Human Disease
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務