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809926

Sigma-Aldrich

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 solution

100 μg/mL in ethanol, ≥98 atom % D, ≥95% (CP)

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About This Item

經驗公式(希爾表示法):
C27D6H38O3
CAS號碼:
分子量::
422.67
EC號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.12

同位素純度

≥98 atom % D

品質等級

化驗

≥95% (CP)

形狀

liquid

濃度

100 μg/mL in ethanol

技術

mass spectrometry (MS): suitable

顏色

colorless

質量偏移

M+6

儲存溫度

−20°C

SMILES 字串

C=C1[C@@H](O)C[C@H](O)C/C1=C/C=C2C(CCC3[C@H](C)CCCC(O)(C([2H])([2H])[2H])C([2H])([2H])[2H])[C@]3(C)CCC/2

InChI

1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23?,24?,25+,27-/m1/s1/i3D3,4D3

InChI 密鑰

GMRQFYUYWCNGIN-LPTLAYIMSA-N

一般說明

1α,25-Dihydroxyvitamin D3 [1,25(OH)2D3], also known as calcitriol, plays a role in calcium and phosphate metabolism in humans. It also regulates insulin secretion and induces cellular differentiation.
1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 is a deuterated vitamin D3 wherein C-26 and C-27 carbon methyl protons are replaced by deuterium.

應用

1α,25-Dihydroxyvitamin D3-26,26,26,27,27,27-d6 can be used as an analytical standard for the quantitative analysis of dihydroxyvitamin D3 concentration in human serum via LC-MS.

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

57.2 °F

閃點(°C)

14 °C


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Quantification of 1, 25-dihydroxyvitamin D2 and D3 in serum using liquid chromatography-tandem mass spectrometry
Clinical Applications of Mass Spectrometry in Biomolecular Analysis, 63(2), 291-300 (2016)
Paola Illesca et al.
Food & function, 11(10), 9086-9102 (2020-10-08)
Nutritional interventions are promising tools for the prevention of obesity. The n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) docosahexaenoic acid (DHA) modulates immune and metabolic responses while the antioxidant hydroxytyrosol (HT) prevents oxidative stress (OS) in white adipose tissue (WAT).
The emerging role of vitamin D3 in women′s health
Khadilkar, SS
The Journal of Obstetrics and Gynecology of India, 63(2), 147?150-147?150 (2013)
Vitamin D3: a helpful immuno-modulator
Di R, et al.
Immunology, 134(2), 123-139 (2011)

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