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Key Documents

LM2212

Avanti

C12 Ceramide

Avanti Research - A Croda Brand LM2212, ethanol solution

同義詞:

N-(dodecanoyl)-sphing-4-enine

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About This Item

經驗公式(希爾表示法):
C30H59NO3
CAS號碼:
分子量::
481.79
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

ethanol solution

包裝

pkg of 1 × 1 mL (LM2212-1EA)

製造商/商標名

Avanti Research - A Croda Brand LM2212

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1

InChI 密鑰

HXFPPRPLRSPNIB-VARSQMIESA-N

一般說明

Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.

生化/生理作用

Ceramide functions as a secondary messenger to initiate apoptosis. It also regulates physiological processes and is accountable for the epidermal permeability barrier in eukaryotic membranes.

包裝

2 mL Amber Glass Sealed Ampule (LM2212-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

55.4 °F - closed cup

閃點(°C)

13.0 °C - closed cup


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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Mammalian Ceramide Synthases
Levy M and Futerman AH
Febs Letters, 62(5), 347-356 (2010)
The enigma of ceramide synthase regulation in mammalian cells
Wegner MS, et al.
Progress in Lipid Research, 63, 93-119 (2016)
Nesli-Ece Sen et al.
International journal of molecular sciences, 20(23) (2019-11-27)
Ataxin-2 (human gene symbol ATXN2) acts during stress responses, modulating mRNA translation and nutrient metabolism. Ataxin-2 knockout mice exhibit progressive obesity, dyslipidemia, and insulin resistance. Conversely, the progressive ATXN2 gain of function due to the fact of polyglutamine (polyQ) expansions
Radiation and ceramide-induced apoptosis
Kolesnick R and Fuks Z
Oncogene, 22(37), 5897-5897 (2003)
Guang-Yi Dai et al.
The Journal of biological chemistry, 295(3), 717-728 (2019-12-11)
Cellular membranes contain many lipids, some of which, such as sphingolipids, have important structural and signaling functions. The common sphingolipid glucosylceramide (GlcCer) is present in plants, fungi, and animals. As a major plant sphingolipid, GlcCer is involved in the formation

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