582231

破伤风类毒素，来源于破伤风梭菌

This tetanus toxoid is prepared by formaldehyde inactivation of tetanus toxin. It retains its antigenic character, but is essentially nontoxic as determined by an LD₅₀ in mice.

• 同義詞: TTx
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 200
• 形狀: lyophilized
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 運輸包裝: ambient
• 儲存溫度: 2-8°C

描述

生化／生理作用

Tetanus Toxoid acts against Clostridium tetani, a gram-positive bacillus that produces a neurotoxin called tetanospasmin. Tetanospasmin prevents the release of an inhibitory neurotransmitter and causes unopposed muscle contractions and spasms. Tetanus toxoid vaccine stimulates the immune system to respond to the vaccine’s antigens. The immune system’s T-lymphocytes (TH2 and B cells) secrete immunoglobulin against the antigen in the vaccine. This immunoglobulin helps to protect against future infections.

警告

毒性：标准处理（A）

外觀

由 100 mM 组氨酸、100 mM NaCl、5% 海藻糖、pH 7.0 冻干而成。

重構

在50µl无菌H₂O水中复溶

其他說明

Wrenger, S., et al. 2000.J. Biol. Chem.275, 22180.
Habermann E. and Goretzki, K. 1985.In Monoclonal Antibodies Against Bacteria (Macario, A.J.L., and Conway de Macario, E. eds.)Academic Press, New York, p.191.
Kozbor, D. and Roder, J.C. 1981.J. Immunol.127, 1275.
Bizzini, B., et al. 1970.Eur. J. Biochem.17, 100.
Largier, J.F. and Joubert, F.J.1956.Biochem.Biophys.Acta20, 407.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable