推薦產品
化驗
≥95%
形狀
liquid
反應適用性
reagent type: linker
密度
1.15 g/cm3 (lit.)
官能基
Boc
amine
carboxylic acid
儲存溫度
−20°C
SMILES 字串
OC(COCCOCCNC(OC(C)(C)C)=O)=O
InChI
1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
InChI 密鑰
OMBVJVWVXRNDSL-UHFFFAOYSA-N
應用
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.
t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
法律資訊
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
相關產品
產品號碼
描述
訂價
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
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