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15369

Sigma-Aldrich

N-Boc-乙二胺

≥98.0% (NT)

同義詞:

N-(2-氨乙基)氨基甲酸叔丁酯, N-Boc-1,2-二氨基乙烷

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About This Item

線性公式:
(CH3)3COCONHCH2CH2NH2
CAS號碼:
分子量::
160.21
Beilstein:
1932330
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98.0% (NT)

反應適用性

reagent type: cross-linking reagent

折射率

n20/D 1.458 (lit.)
n20/D 1.458

bp

72-80 °C/0.1 mmHg (lit.)

密度

1.012 g/mL at 20 °C (lit.)

官能基

Boc
amine

SMILES 字串

NCCNC(OC(C)(C)C)=O

InChI

1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)

InChI 密鑰

AOCSUUGBCMTKJH-UHFFFAOYSA-N

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應用

  • Facile synthesis of new N-(aminocycloalkylene) amino acid compounds:描述N-Boc-乙二胺在2-{[2-(Boc-氨基)乙基]氨基}乙酸苄酯制备中的应用(G Matulevičiūtė et al., 2023)。
  • Synthesis of a new tripod BODIPY dye:报道N-Boc-乙二胺参与化学合成BODIPY染料(H Wang et al., 2022)。
  • Single‐Entity Electrocatalysis:讨论N-Boc-乙二胺在电催化用改性Co3O4纳米颗粒中的应用(T Quast et al., 2021)。

其他說明

乙二胺的单保护衍生物,制备药理活性类似物;引入乙二胺间隔基。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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W S Saari et al.
Journal of medicinal chemistry, 34(10), 3132-3138 (1991-10-01)
Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydrochloride (11) proved to be preferentially toxic to hypoxic EMT6 mammary carcinoma cells. At 1 mM concentration in
E Morier-Teissier et al.
Journal of medicinal chemistry, 36(15), 2084-2090 (1993-07-23)
A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly-His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound
Deborah Sultan et al.
Small (Weinheim an der Bergstrasse, Germany), 14(30), e1703115-e1703115 (2018-07-03)
Focused ultrasound (FUS) technology is reported to enhance the delivery of 64 Cu-integrated ultrasmall gold nanoclusters (64 Cu-AuNCs) across the blood-brain barrier (BBB) as measured by positron emission tomography (PET). To better define the optimal physical properties for brain delivery
Russell D Viirre et al.
The Journal of organic chemistry, 68(4), 1630-1632 (2003-02-15)
An improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt is reported. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate hydrate and furnishes the title compound in near quantitative yield and high purity without chromatography.
Synthesis of N,N-dilactitol ethylenediamine: a versatile spacer for attachment of residualizing labels to protein.
M M Dowd et al.
Analytical biochemistry, 205(2), 369-371 (1992-09-01)

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