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Merck
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重要文件

731129

Sigma-Aldrich

N -异丙基丙烯酰胺

≥99%

同義詞:

NIPAM

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About This Item

線性公式:
H2C=CHCONHCH(CH3)2
CAS號碼:
分子量::
113.16
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

化驗

≥99%

形狀

flakes

bp

89-92 °C/2 mmHg (lit.)

mp

60-63 °C (lit.)
63-67 °C

儲存溫度

2-8°C

SMILES 字串

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)

InChI 密鑰

QNILTEGFHQSKFF-UHFFFAOYSA-N

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一般說明

N-异丙基丙烯酰胺(NIPAM)是一种生物相容性单体单元,由于其对温度敏感的特性,可用于形成刺激反应性聚合物。此类性质包括基于温度的体积和相变——当溶液的温度达到较低的临界溶液温度(LCST)时,会发生变化。

應用

NIPAM可用于制备聚(NIPAM),适用于各种应用,如组织工程,细胞培养、生物医学涂层、药物递送和肌肉再生。

N-异丙基丙烯酰胺还可用作以下方面的关键成分:
  • 基于聚丙烯酸-N-异丙基丙烯酰胺合成自供电多功能有机水凝胶,以实现柔性传感器件。
  • 开发新型柔性稳定凝胶型电解质以实现水性Zn-MnO2电池。
  • 制备聚N-异丙基丙烯酰胺/衣康酸(PNIPAM/IA)共聚水凝胶,用于药物输送应用。
  • 合成聚N异丙基丙烯酰胺(PNIPAM)聚合物,用于开发一类新型聚合物接枝半导体器件。

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Bio-Instructive Scaffolds for Muscle Regeneration: NonCrosslinked Polymers
Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine, 34(9), 161-186 (2017)
Firdaus Yhaya et al.
Macromolecular rapid communications, 33(21), 1868-1874 (2012-08-24)
A block copolymer based on poly(N-isopropyl acrylamide) (PNIPAAm) and a block with a statistical distribution of poly(2-hydroxyethyl acrylate) (PHEA) and repeating unit with carrying β-cyclodextrin was prepared via reversible addition-fragmentation chain transfer (RAFT) polymerization and click reaction. Addition of poly(2-hydroxyethyl
Yamin Li et al.
Biomacromolecules, 13(11), 3877-3886 (2012-09-28)
Polymeric drug nanocarriers integrated with diagnostic and sensing functions are capable of in situ monitoring the biodistribution of chemotherapeutic drugs and imaging/contrasting agents, which enables the establishment of image-guided personalized cancer therapeutic protocols. Responsive multifunctional theranostic nanocarriers possessing external stimuli-tunable
Jason Ng et al.
Environmental science & technology, 53(11), 6436-6443 (2019-05-07)
In the current study, a novel stimuli-responsive hybrid polymer with aluminum hydroxide colloids incorporated into a cationic copolymer of N-isopropylacrylamide and N-[3-(dimethylamino)propyl]methacrylamide was synthesized to enhance the settling and filtration performance of fine clay suspensions. The conformation of the synthesized
Nhung H A Nguyen et al.
Nanoscale research letters, 12(1), 571-571 (2017-10-21)
The most challenging task in the preparation of magnetic poly(N-isopropylacrylamide) (Fe

文章

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

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