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Key Documents

900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

同義詞:

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

經驗公式(希爾表示法):
C14H15F3N2OSi
CAS號碼:
分子量::
312.36
分類程式碼代碼:
12352200
NACRES:
NA.22

化驗

≥95%

形狀

powder or crystals

儲存溫度

−20°C

SMILES 字串

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

應用

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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文章

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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