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Key Documents

900601

Sigma-Aldrich

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

同義詞:

Formyl sulfonyl fluoride alkyne, Probe building block

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About This Item

經驗公式(希爾表示法):
C12H13FO3SSi
CAS號碼:
分子量::
284.38
分類程式碼代碼:
12352200
NACRES:
NA.22

化驗

≥95%

形狀

solid

反應適用性

reaction type: click chemistry

儲存溫度

−20°C

SMILES 字串

O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1

應用

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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文章

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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