900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

• 同義詞: Amino sulfonyl fluoride TMS-alkyne, Probe building block
• 經驗公式（希爾表示法）: C₁₁H₁₄FNO₂SSi
• CAS號碼: 2088828-95-7
• 分子量：: 271.38
• 分類程式碼代碼: 12352200
• NACRES: NA.22

屬性

• 形狀: liquid
• 存貨情形: available only in USA
• 儲存溫度: −20°C
• SMILES 字串: NC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

描述

應用

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他說明

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全資訊

• 象形圖: GHS02
• 訊號詞: Danger
• 危險聲明: H242
• 防範說明: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危險分類: Self-react. C
• 儲存類別代碼: 5.2 - Organic peroxides and self-reacting hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable