900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 同義詞: Bromo sulfonyl fluoride alkyne, Probe building block
• 經驗公式（希爾表示法）: C₁₂H₁₄BrFO₂SSi
• CAS號碼: 2088829-12-1
• 分子量：: 349.29
• MDL號碼: MFCD30737997
• 分類程式碼代碼: 12352200
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: solid
• 反應適用性: reaction type: click chemistry
• 儲存溫度: −20°C
• SMILES 字串: [Si](C)(C)(C)C#Cc1cc(cc(c1)CBr)[S](=O)(=O)F
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)5-4-10-6-11(9-13)8-12(7-10)17(14,15)16/h6-8H,9H2,1-3H3
• InChI 密鑰: QSYGHPYMWBAJRL-UHFFFAOYSA-N

描述

應用

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他說明

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable