推荐产品
生物源
Escherichia coli (O127:B8)
品質等級
形狀
lyophilized powder
純化經由
ion-exchange chromatography
雜質
<1% Protein
<1% RNA
顏色
white to yellow cast
溶解度
water: soluble
運輸包裝
ambient
儲存溫度
2-8°C
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一般說明
该产物从大肠杆菌血清型 O127：B8 中提取，并通过离子交换纯化。源菌株为 ATCC 12740。该 LPS 血清型已经用于脓毒性休克的研究，并且可在大鼠肾小球 masangial 细胞中诱导小鼠巨噬细胞和 PAF 中的 NOS 合成。
應用
脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式（PAMP）的Toll样受体蛋白家族成员Toll样受体4（TLR4）刺激先天性免疫系统细胞。
生化／生理作用
脂多糖（LPS）位于膜的外层，并且在非包封的菌株中暴露在细胞表面上。它们有助于外膜的完整性，并保护细胞免受胆汁盐和亲脂性抗生素的作用。
準備報告
产物可溶于水（5 mg/mL）或细胞培养基（1 mg/mL），产生浑浊的淡黄色溶液。在经过涡旋，并升温至 70-80°C 后，含水盐水变得更浓缩，但仍然浑浊（20mg/mL）。脂多糖分子在每种溶剂中均形成胶束。在水和磷酸盐缓冲盐水中观察到浑浊的溶液。使用有机溶剂，溶液也是浑浊的。甲醇产生具有漂浮物的浑浊悬浮液，而水则产生均匀浑浊的溶液。
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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