推荐产品
生物源
Escherichia coli (O127:B8)
品質等級
無菌
γ-irradiated
產品線
BioXtra
形狀
lyophilized powder
純化經由
gel-filtration chromatography
技術
cell culture | mammalian: suitable
雜質
<1% Protein (Lowry)
溶解度
H2O: 5 mg/mL, slightly hazy
儲存溫度
2-8°C
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應用
来自Escherichia coli 0127:B8脂多糖用于：
- 研究LPS诱导小鼠巨噬细胞存活
- 诱导牛PBMC分泌细胞因子
- 研究LPS诱导促炎环境高易感巨噬细胞细胞凋亡。
- 进行BV2和BV2-LC3细胞自吞噬实验。
- 激活人单核细胞，巨噬细胞和小鼠小胶质细胞
- 诱导293T细胞穿透素-3
脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS及其脂质A部分可通过能够识别常见的病原体相关分子模式（PAMP）的Toll样受体蛋白家族成员Toll样受体4（TLR4）刺激先天性免疫系统细胞。
生化／生理作用
脂多糖（LPS）是革兰氏阴性菌细胞壁的特征组分。LPS和它的脂质A单体通过Toll样受体4（TLR4）激活天然免疫系统细胞。作为免疫原抗原，它增强了对于可溶性抗原的免疫反应。
重構
脂多糖以经γ-射线处理的冻干粉形式提供。如需重悬，可将1 ml无菌的平衡盐溶液或组织培养基加入至小瓶（1 mg）中并轻轻晃动直至粉末溶解。重悬后的产品可采用无菌的平衡盐溶液或组织培养基进一步被稀释至所需的工作浓度。
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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