推荐产品
生物源
Escherichia coli (O55:B5)
品質等級
形狀
lyophilized powder
純化經由
gel-filtration chromatography
雜質
<3% Protein
顏色
white to faint gray
溶解度
water: soluble
運輸包裝
ambient
儲存溫度
2-8°C
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相关类别
一般說明
这种产品是从大肠杆菌中提取的大肠杆菌血清型O55：B5，通过凝胶过滤纯化。源菌株是CDC 1644-70。脂多糖O55：B5已被用于以1纳克/毫升刺激人腹膜巨噬细胞，并以1-100纳克/毫升刺激马腹膜巨噬细胞。
應用
脂多糖（LPS）是革兰氏阴性细菌细胞壁的特征组分。脂多糖及其脂质 A 部分通过 Toll 样受体 4（TLR4）刺激先天免疫系统的细胞，Toll 样受体 4是 Toll 样受体蛋白家族的成员，其识别常见的病原体相关分子模式（PAMP）。
生化／生理作用
脂多糖位于膜的外层，在非包膜菌株中，暴露在细胞表面。它们有助于外膜的完整性，保护细胞免受胆盐和亲脂性抗生素的作用。
準備報告
该产品可溶于水（5毫克/毫升）或细胞培养基（1毫克/毫升），产生一种朦胧的淡黄色溶液。在涡旋并升温至70-80 oC温度后，在盐水中获得了更浓但仍模糊的溶液（20毫克/毫升）脂多糖是在每种溶剂中形成胶束的分子。在水和磷酸盐缓冲盐水中观察到混浊的溶液。有机溶剂不能提供更清晰的溶液。甲醇产生带有漂浮物的混浊悬浮液，而水产生均匀混浊的溶液。
相關產品
产品编号
说明
价格
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 2 Oral
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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