RAB1138

Rat BDNF ELISA Kit

for cell culture supernatants, plasma, and serum samples

• Synonym(s): BDNF, Brain-derived neurotrophic factor
• UNSPSC Code: 41116158
• NACRES: NA.32

Properties

• species reactivity: human, rat
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable
• input: sample type plasma; sample type cell culture supernatant(s); sample type serum sample(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 12 pg/ml
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: rat ... Bdnf(24225)

Description

General description

The brain-derived neurotrophic factor (BDNF) gene is mapped to human chromosome 11p14.1. The gene encodes a precursor protein, proBDNF. Mature BDNF (mBDNF) is synthesized by post-translational cleavage of proBDNF.

This ELISA antibody pair detects rat and human BDNF. Other species are not determined.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Biochem/physiol Actions

Brain-derived neurotrophic factor (BDNF) is involved in hippocampal function and verbal episodic memory in humans. BDNF also plays a vital role in vascular function and participates in angiogenesis via the specific receptor tropomyosin-related kinase B (TrkB). It is involved in the pathogenesis of Alzheimer′s disease.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Safety Information

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class: 8A - Combustible corrosive hazardous materials
• flash_point_f: Not applicable
• flash_point_c: Not applicable