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Key Documents

AB3540P

Sigma-Aldrich

Anti-Monocarboxylate Transporter 1 Antibody

Chemicon®, from rabbit

Synonym(s):

MCT1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC16A1(6566)

Specificity

Recognizes rat Monocarboxylate Transporter 1 (MCT1). The immunogen shows no significant sequence homology with MCT2-8.

SPECIES REACTIVITIES: The immunogen sequence is 93% conserved in hamster, 80% in mouse and only 40% in human. Reactivity with other species has not been confirmed.

Immunogen

A 17 amino acid peptide sequence near the C-terminus of rat MCT1 (Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999).

Application

Detect Monocarboxylate Transporter 1 using this Anti-Monocarboxylate Transporter 1 Antibody validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot: 1-5 μg/mL using ECL. Membrane preps are recommended.



ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Physical form

Liquid in PBS containing 0.1% BSA .

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Evidence for differential regulation of lactate metabolic properties in aged and unloaded rat skeletal muscle.
Shinya Masuda, Tatsuya Hayashi, Tatsuro Egawa, Sadayoshi Taguchi, Shinya Masuda et al.
Experimental Gerontology null
Inhibition of calcineurin increases monocarboxylate transporters 1 and 4 protein and glycolytic enzyme activities in rat soleus muscle.
Masataka Suwa, Hiroshi Nakano, Shuzo Kumagai
Clinical and Experimental Pharmacology & Physiology null
Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer pET imaging study in rats.
Pifferi F, Tremblay S, Croteau E, Fortier M, Tremblay-Mercier J, Lecomte R, Cunnane SC
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Proteomic analysis of membrane proteins expressed specifically in pluripotent murine embryonic stem cells.
Intoh A, Kurisaki A, Yamanaka Y, Hirano H, Fukuda H, Sugino H, Asashima M
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Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier.
Elena V Batrakova, Yan Zhang, Yili Li, Shu Li, Sergei V Vinogradov, Y Persidsky et al.
Pharmaceutical Research null

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