256536

Phosphorus tribromide

99%

• Synonym(s): Phosphorus(III) bromide
• Linear Formula: PBr₃
• CAS Number: 7789-60-8
• Molecular Weight: 270.69
• EC Number: 232-178-2
• MDL number: MFCD00011436
• UNSPSC Code: 12352101
• PubChem Substance ID: 24855534
• NACRES: NA.22

Properties

• vapor pressure: 0.27 psi ( 54 °C)
• Quality Level: 200
• assay: 99%
• form: liquid
• refractive index: n20/D 1.697 (lit.)
• bp: 175 °C (lit.)
• mp: −41.5 °C (lit.)
• density: 2.88 g/mL at 20 °C (lit.)
• SMILES string: BrP(Br)Br
• InChI: 1S/Br3P/c1-4(2)3
• InChI key: IPNPIHIZVLFAFP-UHFFFAOYSA-N

Description

General description

Phosphorus tribromide (PBr₃) is commonly used in Hell-Volhard-Zelinsky halogenation for the α-bromination of carboxylic acids to form the corresponding acyl bromide. It is also useful for the conversion of primary and secondary alcohols to alkyl bromides.

Application

Phosphorus tribromide may be used as a reagent:

• In a novel protocol for synthesizing 7-ethoxy-1-(p-ethylphenoxy)-3,7-dimethyl-2-octene, a synthetic juvenile hormone mimic of trans,trans,cis-10,11-epoxy-7-ethyl-3,11-dimethyltrideca-2,6-dienoate.
• To synthesize 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring.
• To synthesize 1-Bromoundec-1-ene from 10-undecen-1-ol.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H314,H335
• pcodes: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014
• Storage Class: 8B - Non-combustible corrosive hazardous materials
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter