1475008

Novobiocin

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Benzamide, N-[7-[[3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-ß-l-lyxohexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-; (3-methyl-2-butenyl), monohydrate, Streptonivicin
• Wzór empiryczny (zapis Hilla): C₃₁H₃₆N₂O₁₁ · H₂O
• Numer CAS: 56677-21-5
• Masa cząsteczkowa: 630.64
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: novobiocin
• producent / nazwa handlowa: USP
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: −20°C
• InChI: 1S/C31H35N2O11.Na/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29;/h7,9-13,23,25-26,29,34,36H,8H2,1-6H3,(H2,32,39)(H,33,37);/q-1;+1
• Klucz InChI: AXOUUAINTJNFRS-UHFFFAOYSA-N

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

• Enhancing antibiotic effectiveness: Novobiocin is explored as a co-agent in antibacterial strategies, particularly in enhancing the efficacy of other antibiotics like rifampicin against multidrug-resistant bacteria. This underscores its role in combating bacterial resistance and its potential application in developing new antibacterial therapies (Ramirez et al., 2024).


• Gene expression modulation: The study investigates novobiocin′s impact on gene expression related to antibiotic production, demonstrating its utility in biotechnological applications to boost the yield of other clinically important antibiotics. This research highlights its role in understanding and manipulating microbial pathways for enhanced drug production (Zhukrovska et al., 2024).


• Microbial metabolism in animal health: Novobiocin′s effects on microbial nitrogen metabolism in composted poultry litter are assessed, providing insights into its environmental and veterinary applications. This study illustrates its broader applications beyond human medicine, particularly in agricultural and environmental health (Arzola-Alvarez et al., 2022).

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

This product is part of the USP Biologics program.

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302,H317
• Zwroty wskazujące środki ostrożności: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral - Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable