59140-U
SUPELCOSIL™ LC-ABZ (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Synonim(y):
Amino-Benzene-Zone HPLC Column
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About This Item
Polecane produkty
product name
SUPELCOSIL™ LC-ABZ HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Materiały
stainless steel column
agency
suitable for USP L60
linia produktu
SUPELCOSIL™
Właściwości
endcapped
producent / nazwa handlowa
SUPELCOSIL™
opakowanie
1 ea of
zakres etykietowania
12.0% carbon loading
Parametry
≤70 °C temp. limit
400 bar pressure (5801 psi)
metody
HPLC: suitable
dł. × śr. wewn.
15 cm × 4.6 mm
powierzchnia
170 m2/g
pokrycie powierzchni
surface coverage 3.4 μmol/m2
macierz
silica gel, spherical particle platform
fully porous particle
grupa aktywna macierzy
amide, alkyl phase
wielkość cząstki
5 μm
wielkość porów
120 Å
zakres pH
2-7.5
Zastosowanie
food and beverages
metoda separacji
reversed phase
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Opis ogólny
SUPELCOSIL LC-ABZ phase has a unique deactivation technology which provides excellent reversed-phase performance for basic compounds, as well as those that are acidic, polar neutral, and non-polar. Silanol suppressing practices such as using competing amines, operating at high ionic strength, and adjusting mobile phases to pH extremes are typically not required to obtain good peak shape on the LC-ABZ phase.
Zastosowanie
- Validation of a high-performance liquid chromatography method for the assay of and determination of related organic impurities in nevirapine drug substance.: This paper validates a method using the SUPELCOSIL™ LC-ABZ HPLC Column for assessing purity and impurities in HIV medication, showcasing the column′s high specificity and reproducibility (Li et al., 2000).
- A comparative study of the reversed-phase HPLC retention behaviour of S-adenosyl-L-methionine and its related metabolites on Hypersil ODS and Supelcosil LC-ABZ stationary phases.: This comparative study provides insights into the retention behaviors of bioactive compounds on SUPELCOSIL™ LC-ABZ, affirming its versatility and robust performance in complex biochemical separations (Valkó et al., 1993).
Cechy i korzyści
• For acids, bases, zwitterions
• Increased polar retention relative to standard reversed-phases
• Unique selectivity
• Silanol deactivation
• Peak shape, efficiency, and retention are comparable to C8 phases for non-polar analytes
• Increased polar retention relative to standard reversed-phases
• Unique selectivity
• Silanol deactivation
• Peak shape, efficiency, and retention are comparable to C8 phases for non-polar analytes
Informacje prawne
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
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Zastosowanie
Numer produktu
Opis
Cennik
kartridż do prekolumny
Numer produktu
Opis
Cennik
produkt powiązany
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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K Valkó et al.
Journal of pharmaceutical and biomedical analysis, 11(4-5), 361-366 (1993-04-01)
S-Adenosyl-L-methionine (SAM) and its metabolites S-adenosyl-L-homocysteine (SAH) and methyl-thioadenosine (MTA) are endogenous compounds that are heavily involved in a variety of biochemical processes, and have therefore been the target for several assays in body fluids and tissues. Reversed-phase chromatographic behaviour
Q C Li et al.
Journal of chromatographic science, 38(6), 246-254 (2000-07-13)
Nevirapine (Viramune), a dipyridiodiazepinone, is a potent and highly specific nonnucleoside inhibitor of HIV-1 reverse transcriptase. This paper describes the validation of a specific, sensitive, and stability-indicating high-performance liquid chromatography method for the assay and determination of related organic impurities
Murali Pendela et al.
Journal of separation science, 32(20), 3418-3424 (2009-09-19)
Streptomycin (SM) is composed of streptidine, streptose and N-methyl glucosamine sugar moieties. For the determination of SM and its related substances, an ion-pair LC-UV detection method using a Supelcosil LC-ABZ column was developed previously. While analyzing commercial samples, several unknown
D Korakas et al.
Journal of pharmaceutical and biomedical analysis, 12(9), 1141-1145 (1994-09-01)
A series of biologically active peptides and their conjugates with lipidic amino acids were investigated by systematic change of the mobile phase composition using traditional octadecylsilica stationary phase and the newly developed Supelcosil LC-ABZ column. The mobile phases contained various
Ana B Baranda et al.
Journal of chromatography. A, 1031(1-2), 275-280 (2004-04-03)
A high-performance liquid chromatographic method with electrochemical detection was developed for the simultaneous determination of five 1,4-dihydropyridines: amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine. These drugs are widely used in the treatment of hypertension, angina pectoris and the therapy of cerebrovascular
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