16018AST
Astec® CHIROBIOTIC® T2 Chiral (5 μm) HPLC Columns
L × I.D. 10 cm × 2.1 mm, HPLC Column
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About This Item
Kod UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Polecane produkty
product name
Astec® CHIROBIOTIC® T2 Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 2.1 mm
Materiały
stainless steel column
agency
suitable for USP L63
opis
HPLC column
linia produktu
Astec®
opakowanie
pkg of 1 ea
producent / nazwa handlowa
Astec®
Parametry
0-45 °C temperature
241 bar pressure (3500 psi)
metody
HPLC: suitable
LC/MS: suitable
dł. × śr. wewn.
10 cm × 2.1 mm
macierz
high-purity silica gel particle platform
fully porous particle
wielkość cząstki
5 μm
wielkość porów
200 Å
operating pH range
3.8-6.8
metoda separacji
chiral
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Opis ogólny
CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.
- Bonded phase: Teicoplanin
- Operating pH range: 3.8 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)
Informacje prawne
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Chromatography Liquid Chiral Separations
Xiao, T.L., et al.
Encyclopedia of Separation Science, 1-15 (2000)
Chromatographic Separations and Analysis: Macrocyclic Glycopeptide Chiral Stationary Phases
Berthod, A.
Comprehensive Chirality, 8, 227-262 (2012)
Ping Sun et al.
Journal of molecular structure, 890(1-3), 75-80 (2008-11-12)
A high performance liquid chromatographic method using macrocyclic glycopeptide chiral stationary phases (CSPs) was used to separate enantiomers of seven ruthenium(II) polypyridyl complexes. Among the five different CSPs, the Chirobiotic T2 was most effective and baseline separated all complexes. All
Chris Hamman et al.
Journal of chromatography. A, 1305, 310-319 (2013-07-31)
A rapid screening method to identify the best conditions for chiral separations is described. We analyzed a representative set of 80 racemic compounds against 25 different chiral stationary phases with three different mobile phases to identify the combination of columns
Sarangan Ravichandran et al.
Journal of chromatography. A, 1269, 218-225 (2012-08-25)
The enantioselective separations of the chiral oxazaphosphorines (R,S)-ifosfamide (IF), (R,S)-2-N-dechloroethyl-IF (2-DCE-IF) and (R,S)-3-N-dechloroethyl-IF (3-DCE-IF) were achieved on teicoplanin-based chiral stationary phase using isopropanol:methanol (60:40, v/v) as the mobile phase. Computational models of the teicoplanin and teicoplanin aglycon (TAG) chiral selectors
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