SRP6172
IL-4 human
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
Synonim(y):
B-cell stimulatory factor 1 (BSF-1), BCGF, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Kod UNSPSC:
12352202
NACRES:
NA.32
Polecane produkty
pochodzenie biologiczne
human
rekombinowane
expressed in HEK 293 cells
Próba
≥95% (SDS-PAGE)
Postać
lyophilized
masa cząsteczkowa
(14 and 19 kDa, monomer)
opakowanie
pkg of 10 μg
metody
cell culture | mammalian: suitable
numer dostępu NCBI
Warunki transportu
dry ice
temp. przechowywania
−70°C
informacje o genach
human ... IL4(3565)
Opis ogólny
Interleukin-4 (IL-4) is a pleiotropic cytokine and a potent lymphoid cell growth factor. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The gene encoding this protein is localized on human chromosome 5q31.1. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Działania biochem./fizjol.
Interleukin-4 (IL-4) stimulates the growth and survivability of certain B cells and T cells. The interleukin 4 receptor also binds to interleukin-13 (IL-13), which may contribute to many overlapping functions of this cytokine and IL-13. STAT6 (signal transducer and activator of transcription-6) has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This protein exhibits anti-inflammatory responses and has a role in immune processes by protecting against intracellular pathogens.
Postać fizyczna
Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.
Uwaga dotycząca przygotowania
Centrifuge the vial prior to opening.
Rekonstytucja
Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
This page may contain text that has been machine translated.
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.
Masz już ten produkt?
Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Klienci oglądali również te produkty
Interleukin 4 mediates autocrine growth of helper T cells after antigenic stimulation.
Fernandez-Botran R
Proceedings of the National Academy of Sciences of the USA, 83(24), 9689-9693 (1986)
Interleukin 4 inhibition as a potential therapeutic in pemphigus.
Tavakolpour S and Tavakolpour V
Cytokine, 77, 189-195 (2016)
D G Marsh et al.
Science (New York, N.Y.), 264(5162), 1152-1156 (1994-05-20)
Sib-pair analysis of 170 individuals from 11 Amish families revealed evidence for linkage of five markers in chromosome 5q31.1 with a gene controlling total serum immunoglobulin E (IgE) concentration. No linkage was found between these markers and specific IgE antibody
Masanori Kobayashi et al.
Cancer immunology, immunotherapy : CII, 63(8), 797-806 (2014-04-30)
Dendritic cell (DC)-based cancer vaccines may have a significant benefit to patients with advanced pancreatic cancer. However, variations among clinical studies make it difficult to compare clinical outcomes. Here, we identified factors that determined the clinical benefits by analyzing data
Michelle A Favila et al.
Journal of immunology (Baltimore, Md. : 1950), 192(12), 5863-5872 (2014-05-09)
Leishmania major-infected human dendritic cells (DCs) exhibit a marked induction of IL-12, ultimately promoting a robust Th1-mediated response associated with parasite killing and protective immunity. The host cell transcription machinery associated with the specific IL-12 induction observed during L. major
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
Skontaktuj się z zespołem ds. pomocy technicznej